5-CHLORO-1H-PYRAZOLO[4,3-D]PYRIMIDINE

5-CHLORO-1H-PYRAZOLO[4,3-D]PYRIMIDINE - Names and Identifiers

Name	5-Chloro-1H-pyrazolo[4,3-d]pyrimidine
Synonyms	5-Chloropyrazolo[4,3-d]pyrimidine 5-CHLORO-1H-PYRAZOLO[4,3-D]PYRIMIDINE 5-Chloro-1H-pyrazolo[4,3-d]pyrimidine 1H-Pyrazolo[4,3-d]pyrimidine, 5-chloro- 1H-Pyrazolo[4,3-d]pyriMidine, 5-chloro-
CAS	633328-98-0
InChI	InChI=1S/C5H3ClN4/c6-5-7-1-4-3(9-5)2-8-10-4/h1-2H,(H,8,10)

5-CHLORO-1H-PYRAZOLO[4,3-D]PYRIMIDINE - Physico-chemical Properties

Molecular Formula	C5H3ClN4
Molar Mass	154.56
Density	1.653±0.06 g/cm3(Predicted)
pKa	6.68±0.50(Predicted)
Storage Condition	2-8°C

5-CHLORO-1H-PYRAZOLO[4,3-D]PYRIMIDINE - Introduction

5-Chloro-1H-pyrazolo[4,3-d]pyrimidine is an organic compound with the chemical formula C7H4ClN3. It is a white crystalline solid with a strong odor. The following is a description of the nature, use, preparation and safety information of 5-Chloro-1H-pyrazolo[4,3-d]pyrimidine:

Nature:
-Appearance: White crystalline solid
-Melting Point: 209-210°C
-Stability: stable, but avoid contact with strong oxidants
-Solubility: Slightly soluble in water, soluble in most organic solvents

Use:
-Chemical reagents: used in organic synthesis, catalyst preparation and other chemical research fields.
-Drug intermediates: used to synthesize some drugs, such as anti-cancer drugs.

Preparation Method:
5-Chloro-1H-pyrazolo[4,3-d]pyrimidine can be prepared by the following method:
-Reaction of 3-aminopyrazolo [4,3-d] pyrimidine with sulfuryl chloride to obtain 5-sulfonyl-3-aminopyrazolo [4,3-d] pyrimidine.
-5-Sulfoyl-3-aminopyrazolo [4,3-d]pyrimidine is reacted with cuprous chloride to give 5-Chloro-1H-pyrazolo[4,3-d]pyrimidine.

Safety Information:
- 5-Chloro-1H-pyrazolo[4,3-d]pyrimidine are irritating and toxic and should be avoided by inhalation, contact with skin and eyes.
-Wear appropriate protective gloves, glasses and a protective mask to ensure good ventilation during use.
-If contact or inhalation occurs, immediately flush the affected area with plenty of water and seek medical help immediately.
-Please store according to the correct storage method and avoid contact with flammable substances and strong oxidants.

Last Update：2024-04-09 15:17:59